An evaluation of venous thromboembolism by whole-body enhanced CT scan for critical COVID-19 pneumonia with markedly rises of coagulopathy related factors: a case series study

Abstract Background Coronavirus disease (COVID-19) pneumonitis associated with severe respiratory failure has a high mortality rate. Based on recent reports, the most severely ill patients present coagulopathy, and disseminated intravascular coagulation (DIC)-like massive clot formation is frequently observed. Coagulopathy emerged as significant contributor to thrombotic complications. Although recommendations have been made for anticoagulant use COVID-19, no guidelines specified. Case summary We describe four cases of critical COVID-19 thrombosis detected by enhanced CT scan. The findings all demonstrated typical pulmonary embolism or deep venous thrombus without exacerbation. Two died due COVID-19. Discussion Previous reports suggested coagulopathy signs main pathological feature but previous focused evaluated whole-body Changes in hemostatic biomarkers, represented an increase D-dimer fibrin/fibrinogen degradation products, indicated that essence was fibrin formation. there were clinical symptoms related their prognosis, COVID-19-induced systemic Conclusions Therapeutic dose anticoagulants should be considered because induced aggressive follow-up whole body scan thromboembolism (VTE) necessary.